What is AIRR-seq?

AIRR-seq (Adaptive Immune Receptor Repertoire sequencing) is a high-throughput sequencing method used to profile the diverse B-cell and T-cell receptor repertoires. It quantifies clonotypes, diversity, and somatic hypermutation, enabling studies of immune responses, autoimmunity, and immuno-oncology. This technique is widely applied in immunology, vaccine development, oncology, and autoimmune disease research.